Typical pre-seed round size for biotech startups in the US
Based on 200 Form D filings by United States biotech issuers at pre-seed stage, filed Nov 2024 – Oct 2026. Updated monthly. Change any segment to compare.
The numbers
- Median pre-seed raise: $192k
- Middle half of rounds: $69k – $485k
- Filings in sample: 200
- Rounds under $1M: 90%
- Rounds over $5M: 0%
- Updated Oct 2026
Read this number carefully
Form D undercounts small SAFE rounds and rounds that rely on other exemptions. Treat the median as a ceiling for "typical", not a target.
Compare segments
Biotech · Pre-seed · Boston ($470k)