Typical pre-seed round size for biotech startups in Boston

Based on 17 Form D filings by Boston biotech issuers at pre-seed stage, filed Nov 2024 – Oct 2026. Updated monthly. Change any segment to compare.

The numbers

  • Median pre-seed raise: $470k
  • Middle half of rounds: $105k – $1.1M
  • Filings in sample: 17
  • Rounds under $1M: 71%
  • Rounds over $5M: 0%
  • Updated Oct 2026

Read this number carefully

Form D undercounts small SAFE rounds and rounds that rely on other exemptions. Treat the median as a ceiling for "typical", not a target.

Compare segments

Biotech · Pre-seed · Bay Area ($250k)

Biotech · Pre-seed · Research Triangle ($332k)

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