Typical seed round size for biotech startups in the US

Based on 402 Form D filings by United States biotech issuers at seed stage, filed Nov 2024 – Oct 2026. Updated monthly. Change any segment to compare.

The numbers

  • Median seed raise: $2M
  • Middle half of rounds: $817k – $4.3M
  • Filings in sample: 402
  • Rounds under $1M: 29%
  • Rounds over $5M: 18%
  • Updated Oct 2026

Read this number carefully

Form D undercounts small SAFE rounds and rounds that rely on other exemptions. Treat the median as a ceiling for "typical", not a target.

Compare segments

Biotech · Seed · Boston ($4.2M)

Biotech · Seed · Bay Area ($3.9M)

Biotech · Seed · San Diego ($1.9M)

Biotech · Seed · New York ($2.5M)

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